Emerging progress in understanding left-sided and right-sided colorectal cancer
10.3969/j.issn.1000-8179.2018.22.987
- VernacularTitle:左右半结肠癌研究进展
- Author:
Yan WEI
1
;
Liu YANG
;
Wei YUNWEI
Author Information
1. 哈尔滨医科大学附属第一医院肿瘤腔镜外科 哈尔滨市150001
- Keywords:
colorectal cancer;
tumor primary location;
epidemiology;
molecular mechanism;
gut microbiota
- From:
Chinese Journal of Clinical Oncology
2018;45(22):1155-1159
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is one of the most common malignant tumors. According to the primary site of the tumor, the morbidity, etiology, molecular biological characteristics, clinical features, and gut microbiota of patients are different. This review focuses on the characteristics of colorectal cancer according to the tumor location and describes the newest discoveries in molecular biology, gut mi-crobiota, and imunotherapy. Different molecular biological characteristics lead to differences in clinical treatment response, leading to differences in clinical prognosis. Deep understanding of the characteristics of colorectal cancer according to tumor location provides further theoretical basis for improving clinical treatment.