Clinical analysis of lung transplantation from donors combined with pulmonary contusion
10.3969/j.issn.1674-7445.2018.01.008
- VernacularTitle:合并肺段挫伤供肺肺移植的临床疗效分析
- Author:
Shugao YE
1
;
Huixing LI
;
Feng LIU
;
Dong LIU
;
Jingyu CHEN
Author Information
1. 南京医科大学附属无锡市人民医院 江苏省器官移植重点实验室
- Keywords:
Pulmonary contusion;
Lung transplantation;
End-stage lung disease;
Chronic obstructive pulmonary disease (COPD);
Primary graft dysfunction (PGD);
Oxygenation index;
Mechanical ventilation;
Vitro repair;
Extracorporeal membrane oxygenation (ECMO)
- From:
Organ Transplantation
2018;9(1):58-62
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the efficacy and prognosis of lung transplantation from donors combined with pulmonary contusion on the treatment of patients with end-stage lung disease. Methods Clinical data of 73 cases of donors and recipients were collected. The donors and recipients were divided into contusion group (23 cases of donors and recipients, with a maximum diameter of contusion in 5-8 cm) and standard group (50 cases of donors and recipients) depending on combined pulmonary contusion. Major clinical indicators [postoperative oxygenation index, duration of mechanical ventilation and chest tube drainage and incidence of primary graft dysfunction (PGD)] and prognosis of the recipients in both groups were compared. Results The recipients in both groups presented no significant difference in postoperative oxygenation index, duration of mechanical ventilation and chest tube drainage and incidence of PGD (all P>0.05). The postoperative 1-year survival of the recipients in standard group and contusion group was 74％ and 83％, which presented no statistically significant difference (P>0.05). Conclusions The efficacy and prognosis of lung transplantation from donors combined with pulmonary contusion (with a maximum diameter of 5-8 cm) are comparable to those of lung transplantation from standard donors.
