Clinical research of intravitreal injection of Conbercept combined with different methods in the treatment of neovascular glaucoma
- Author:
Li-Ping Wang
1
Author Information
- Publication Type:Journal Article
- Keywords: neovascular glaucoma, conbercept, intravitreal injection, complex trabeculectomy, panretinal photocoagulation
- From: International Eye Science 2017;17(2):332-334
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To observe the clinical effects of intravitreal injection of conbercept combined with complex trabeculectomy and panretinal photocoagulation(PRP)in the treatment of neovascular glaucoma.
METHODS: Eleven patients(11 eyes)with neovascular glaucoma were injected with conbercept 0.50mg/0.05mL in vitreous chamber. Complex trabeculectomy was performed after the neovascularization dissipated, and PRP was performed in all cases at the right time. The follow-up time was 6mo. The vision, intraocular pressure(IOP)and complications were observed after complex trabeculectomy.
RESULTS: The IOP were all decreased at 1wk, 1, 3 and 6mo after operation, and the difference was statistically significant(P<0.01). After 6mo, the best-corrected visual acuity of 2 eyes(18%)was improved, 8 eyes(73%)were stable, and 1 eye(9%)was declined. The postoperative complications included hyphema, shallow anterior chamber, and vitreous hemorrhage.
CONCLUSION: Intravitreous injection of conbercept combined with complex trabeculectomy and PRP can control the IOP and preserve the visual function effectively in patients with neovascular glaucoma.
