Sero-prevalence of Hepatitis B Virus Surface Antigen and Antibody in High School Students in Chungju-city.
- Author:
Hyeongsu KIM
1
;
Kun Sei LEE
;
Soung Hoon CHANG
;
Suekyung PARK
;
Cheongsik KIM
;
Chang Hee LEE
;
Hyuk Jung KWEON
;
Soon Sup CHUNG
Author Information
1. Department of Preventive Medicine, College of Medicine, Konkuk University, Korea. kunsei_lee@kku.ac.kr
- Publication Type:Original Article
- Keywords:
Hepatitis B;
HBsAg;
HBsAb
- MeSH:
Antigens, Surface;
Female;
Hemagglutination;
Hepatitis B Surface Antigens;
Hepatitis B virus*;
Hepatitis B*;
Hepatitis*;
Humans;
Infant, Newborn;
Korea;
Male;
Parturition;
Vaccination
- From:Korean Journal of Epidemiology
2002;24(2):107-112
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: Since Korea has been known to be one of the endemic area for hepatitis B virus(HBV) infection, vaccination for HBV has been recommended for all neonates in Korea. After starting vaccination in 1983, the change of sero-positivity of HBsAg and HBsAb is expected. This study was carried out to investigate the seropositive rate of hepatitis B virus surface antigen and antibody in high school freshmen students in Chungju-city. METHODS AND MATERIALS: From 1998 to 2001, a total of 11,735 who were born in 1982 to 1986, were enrolled in this study. HBsAg and anti-HBs were tested by reversed passive hemagglutination and passive hemagglutination, respectively. PESULTS: The study population was 11,735 students who were composed of 5,813 males (49.6%) and 5,914 females (50.4%). The HBsAg sero-positivity of male and female students was 3.25% (n=381) and 2.59% (n=153) respectively. The anti-HBs sero-positivity of male and female students was 62.2% (n=3,154) and 64.1% (n=2,969) respectively. There are significant difference observed in comparison of HBsAg and anti-HBs seropositivity according to sex (p<0.05). From 1982 to 1986 on birth year, anti-HBs sero-positivity has been increased significantly from 63.3% to 73.3%. But the change of HBsAg sero-positivity has not been changed significantly. CONCLUSIONS: As compared with previous studies of HBsAg and anti-HBs, the sero-positive rate of HBsAg has not been changed but that of HBsAb has been increased significantly. This result revealed that the effect of HBV vaccination program was successful.
