A Case of Fulminant Type 1 Diabetes Mellitus in an Elderly Patient.
10.4093/jkd.2015.16.3.225
- Author:
Seung Min WOO
1
;
Seung Hyun HONG
;
Sung Yun LEE
;
Su Heui LEE
;
Duc Ky LEE
;
Sae Jeong YANG
Author Information
1. Departments of Internal Medicine, Daerim Saint Mary's Hospital, Seoul, Korea. yangsj1977@naver.com
- Publication Type:Case Report
- Keywords:
Diabetes mellitus;
Diabetic ketoacidosis;
Type 1
- MeSH:
Aged*;
Antibodies;
Autoimmunity;
Blood Glucose;
C-Peptide;
Diabetes Mellitus;
Diabetes Mellitus, Type 1*;
Diabetic Ketoacidosis;
Follow-Up Studies;
Glutamate Decarboxylase;
Humans;
Insulin;
Japan;
Korea;
Middle Aged;
Myalgia;
Polyuria;
Reference Values;
Thirst
- From:Journal of Korean Diabetes
2015;16(3):225-229
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Insulin deficiency due to destruction of pancreatic beta-cells is a typical characteristic of type 1 diabetes mellitus (DM). In 2000 Imagawa proposed a novel diagnostic model defining "fulminant type 1 DM" as developing rapidly without any evidence of autoimmunity, and ever since there have been many reports regarding the matter in Japan. In 2004, the first fulminant type 1 diabetes case was reported in Korea; however, there have been few reports since then. We present a case of a 60-year-old man who suffered from excessive thirst and polyuria after myalgia. Laboratory findings revealed a high blood glucose level and evidence of diabetic ketoacidosis, but the HbA1c level was within the normal range. The serum C-peptide level was very low and antibodies to glutamic acid decarboxylase were negative. These findings suggested fulminant type 1 diabetes. This patient has shown improvement in symptoms and examination results without complications after being treated with insulin therapy with hydration, throughout 6-months follow-up period.
