A Study of the Relationships between the Ratio of 2nd to 4th Digit Length and Cerebral Laterality.
- Author:
Ahyoung KIM
1
;
Seongkyun KIM
;
Jinyoung YOUN
;
Jaeseung JEONG
;
Joo Ho LEE
;
Jeong Ho CHAE
;
Yu Sang LEE
Author Information
1. Yong-In Mental Hospital, Yongin, Korea. yusanglee@gmail.com
- Publication Type:Original Article
- Keywords:
2nd to 4th digit ratio(2D:4D);
EEG coherences;
Cerebral laterality
- MeSH:
Electroencephalography;
Eye;
Female;
Fingers;
Humans;
Schizophrenia;
Testosterone
- From:Journal of the Korean Society of Biological Psychiatry
2011;18(1):25-35
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: Cerebral laterality is thought to be an important marker for neurodevelopment. Prenatal testosterone could influence both cerebral laterality and 2nd to 4th finger length ratio(2D:4D). EEG coherence and 2D:4D were examined to investigate the relationship between prenatal testosterone level and cerebral laterality. METHODS: EEG was recorded in 24 healthy subjects in the eyes closed resting state. Differences in 2D:4D finger ratio were used to discriminate "masculine finger type" and "feminine finger type" groups. The 2D:4D ratio was lower and greater than one for the "masculine finger type" group and "feminine finger type" group, respectively. We used coherence analysis to estimate the cortical functional connectivity. RESULTS: There were statistically meaningful relationships among cerebral functional connectivity, sex and finger ratio. Man and masculine finger type group showed higher intra-hemispheric coherence than those of woman and feminine finger type group. Woman and feminine finger type group showed higher inter-hemispheric coherence than those of man and masculine finger type group. CONCLUSIONS: These results imply that prenatal testosterone might act as important determinants of cerebral laterality. Further examination of the relationship between 2D:4D and EEG coherence in schizophrenia could give some clues for the neurodevelopmental hypothesis of schizophrenia genesis.
