- Author:
Jae Bum JUN
1
Author Information
- Publication Type:Review
- Keywords: Liver Abscess; Klebsiella pneumoniae; C-reactive protein
- MeSH: Abscess; Asia; C-Reactive Protein; Drainage; Drug Resistance, Microbial; Early Diagnosis; Endophthalmitis; Fever; Humans; Klebsiella pneumoniae*; Klebsiella*; Korea; Liver Abscess*; Liver*; Lung; Meningitis; Phenotype; Prevalence; Serogroup; Taiwan
- From:Infection and Chemotherapy 2018;50(3):210-218
- CountryRepublic of Korea
- Language:English
- Abstract: Since the mid 1980s, the prevalence of liver abscess caused by hypervirulent Klebsiella pneumoniae strain has increased in Asia, particularly in Taiwan and Korea. This strain is mostly K1 or K2 serotype, and has hypercapsular and hypermucoid phenotypes. Most infections are community acquired, and patients rarely have a hepatobiliary disease prior to infection. Clinical manifestations are characterized by fever and high C-reactive protein, and metastatic infections, such as septic emboli in the lung and endophthalmitis and meningitis are frequently observed. Antibiotic resistance is rare. Antibiotic treatment and abscess drainage are needed, and early diagnosis and treatment of endophthalmitis is also important.

