A Case of Granulocytic Sarcoma in the Brain of a Patient with Acute Erythroleukemia.
10.5045/kjh.2008.43.4.272
- Author:
Jae Hoon CHEONG
1
;
Bo Ran KWON
;
Mi Ra KIM
;
Mu Gon SONG
;
Young Mi SEOL
;
Young Jin CHOI
;
Ho Jin SHIN
;
Joo Seop CHUNG
;
Goon Jae CHO
Author Information
1. Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea. gicho@pusan.ac.kr
- Publication Type:Case Report
- Keywords:
Leukemia;
Erythroblastic;
Acute;
Sarcoma;
Myeloid;
Brain
- MeSH:
Brain;
Cerebellum;
Dysarthria;
Headache;
Humans;
Karyotype;
Leukemia;
Leukemia, Erythroblastic, Acute;
Leukemia, Myeloid, Acute;
Magnetic Resonance Imaging;
Middle Aged;
Nausea;
Neoplasm Metastasis;
Sarcoma;
Sarcoma, Myeloid;
Vomiting
- From:Korean Journal of Hematology
2008;43(4):272-275
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Granulocytic sarcoma is a localized tumor that's composed of immature granulocytic cells and this is more common in patient with 8;21 translocation. We present here a case in a 64-year-old man who was diagnosed with acute myelogenous leukemia (erythroleukemia) that had a complex hyperdiploid karyotype. While he underwent chemotherapy, he developed nausea, vomiting, headache and dysarthria. After several diagnostic work-ups, granulocytic sarcoma in the cerebellum and leptomeningeal metastasis of his leukemia were found on the magnetic resonance imaging and the cerebrospinal fluid cytology.
