Comparing 18F-Fluorodeoxyglucose Positron Emission Tomography and Video-assisted Thoracoscopic Surgery in the Evaluation of Small Pulmonary Nodules in Patients with a History of Malignancy.
- Author:
Hong Kyu LEE
1
;
Sung Woo CHO
;
Hee Sung LEE
;
Kun Il KIM
;
Hyoung Soo KIM
;
Seong Joon CHO
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Sacred Heart Hospital, Hallym University College of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Video-assisted thoracic surgery;
Biopsy;
Positive emission tomography
- MeSH:
Adenocarcinoma;
Adenocarcinoma, Bronchiolo-Alveolar;
Biopsy;
Breast;
Early Diagnosis;
Electrons;
Female;
Fibrosis;
Follow-Up Studies;
Head;
Humans;
Hyperplasia;
Liver;
Male;
Neck;
Neoplasm Metastasis;
Ovary;
Pneumonia;
Positron-Emission Tomography;
Stomach;
Thoracic Surgery, Video-Assisted;
Tuberculosis, Pulmonary;
Urinary Bladder;
Uterus
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2012;45(1):35-39
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The aims of the study were to determine the accuracy of fluorodeoxyglucose positron emission tomography (FDG-PET) in detecting pulmonary metastasis through video-assisted thoracoscopic surgery (VATS), a technique that allows the excisional biopsy of small pulmonary nodules in patients with known malignancies. MATERIALS AND METHODS: Between October 2007 and April 2010, 28 patients with known malignancies and small pulmonary nodules underwent VATS excisional biopsies. All patients were in follow-up for a previously treated malignancy. The malignancies included the following: colorectum (9), breast (6), head and neck (5), stomach (3), lymph (1), ovary (1), uterus (1), bladder (1), and liver (1). RESULTS: There were 16 men and 12 women whose mean age was 56.7 years old (range, 38 to 77 years). The sizes of the mean nodules removed were 11.3 mm (range, 7 to 21 mm). Diagnoses included metastatic (11), bronchioloalveolar carcinoma (1), primary adenocarcinoma (1), pulmonary tuberculosis (6), fibrosis (5), organizing pneumonia (3), lymphoid hyperplasia (1). Among these lesions, 46.4% were malignant. CONCLUSION: True positive FDG-PET was 39.2%. FDG-PET is not a sensitive test in the evaluation of patients with a history of an extrathoracic malignancy and newly diagnosed small pulmonary nodules. VATS excision allows the early diagnosis of small pulmonary nodules, with low morbidity, in patients with known malignancies.
