Clinical Usefulness of Aripiprazole Treatment in a Girl with Prader-Willi Syndrome and Psychosis.
10.9758/cpn.2018.16.4.497
- Author:
Wolfgang BRIEGEL
1
Author Information
1. Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Leopoldina Hospital, Schweinfurt, Germany. wbriegel@leopoldina.de
- Publication Type:Case Report
- Keywords:
Prader-Willi syndrome;
Aripiprazole;
Psychosis;
Adolescent;
Case reports
- MeSH:
Adolescent;
Adult;
Aripiprazole*;
Female*;
Humans;
Prader-Willi Syndrome*;
Psychotic Disorders*;
Weight Gain
- From:Clinical Psychopharmacology and Neuroscience
2018;16(4):497-500
- CountryRepublic of Korea
- Language:English
-
Abstract:
Prader-Willi syndrome (PWS) is a quite rare multi-systemic genetic disorder strongly associated with psychiatric illness in adults, especially psychosis. This report presents a 16-year-old female with PWS and symptoms of brief psychotic disorder with a complete resolution of symptoms under aripiprazole medication. However, an exacerbation occurred after aripiprazole reduction. Apart from a weight gain of about 2 kg over the course of two years, no adverse effects could be found. This first report on the use of aripiprazole in a subject with PWS and psychosis suggests that aripiprazole might be a promising treatment approach in this distinct group of patients.
