Cost-Effectiveness of Voluntary HIV Testing Strategies in a Very Low-Prevalence Country, the Republic of Korea.
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3346/jkms.2018.33.e304
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Young Hwa LEE
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Ji Hwan BANG
			        		
			        		;
		        		
		        		
		        		
			        		Sang Min PARK
			        		
			        		;
		        		
		        		
		        		
			        		Cho Ryok KANG
			        		
			        		;
		        		
		        		
		        		
			        		Sung Il CHO
			        		
			        		;
		        		
		        		
		        		
			        		Myoung don OH
			        		
			        		;
		        		
		        		
		        		
			        		Jong Koo LEE
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Epidemiology, Seoul National University Graduate School of Public Health, Seoul, Korea.
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		HIV Screening Test;
			        		
			        		
			        		
				        		Cost-effectiveness Analysis;
			        		
			        		
			        		
				        		Korea
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Cost-Benefit Analysis;
				        		
			        		
				        		
					        		Diagnosis;
				        		
			        		
				        		
					        		Enzyme-Linked Immunosorbent Assay;
				        		
			        		
				        		
					        		HIV Infections;
				        		
			        		
				        		
					        		HIV*;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Korea;
				        		
			        		
				        		
					        		Mass Screening;
				        		
			        		
				        		
					        		Prevalence;
				        		
			        		
				        		
					        		Public Health;
				        		
			        		
				        		
					        		Republic of Korea*
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:Journal of Korean Medical Science
	            		
	            		 2018;33(46):e304-
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	BACKGROUND: The Republic of Korea has a very low prevalence of human immunodeficiency virus (HIV) infection, but the number of new HIV diagnoses has steadily risen, strongly indicating a large number of undetected HIV infections. Thus, it is important for Korean public health authorities to adopt and encourage cost-effective HIV detection tools, such as rapid HIV screening tests. In this study, we aimed to evaluate the cost-effectiveness of enzyme-linked immunosorbent assays (ELISA) and rapid tests in a public health center (PHC) setting. METHODS: We developed a decision analytic model to assess the per-examinee cost and the cost-effectiveness of identifying HIV patients in a PHC setting using two HIV testing strategies: conventional HIV screening by ELISA versus rapid HIV testing. Analysis was performed in two scenarios: HIV testing in an average-risk population and in a high-risk population. RESULTS: Compared to the ELISA, the rapid test was cost-saving and cost-effective. The per-examinee cost was USD 1.61 with rapid testing versus USD 3.38 with ELISA in an average-risk population, and USD 4.77 with rapid testing versus USD 7.62 with ELISA in a high-risk population. The cost of identifying a previously undiagnosed HIV case was USD 26,974 with rapid testing versus USD 42,237 with ELISA in an average-risk population, and USD 153 with rapid testing versus USD 183 with ELISA in a high-risk population. CONCLUSION: Rapid testing would be more cost-effective than using conventional ELISA testing for identifying previously undiagnosed HIV-infected cases in Korea, a country with extremely low HIV prevalence.