A Case of Focal Acral Hyperkeratosis with Autosomal Dominant Inheritance.
- Author:
Ji Yeon HONG
1
;
Joon Hyuk SUH
;
Kapsok LI
;
Seong Jun SEO
Author Information
1. Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea. drseo@hanafos.com
- Publication Type:Case Report
- Keywords:
Autosomal dominant;
Focal acral hyperkeratosis;
Marginal popular acrokeratoderma
- MeSH:
Adult;
Dermis;
Diagnosis;
Epidermis;
Family Characteristics;
Fingers;
Foot;
Hand;
Humans;
Wills*
- From:Korean Journal of Dermatology
2018;56(7):443-446
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Focal acral hyperkeratosis (FAH) is a rare genodermatosis inherited by autosomal dominant transmission; however, some sporadic cases have also been reported. FAH is characterized by multiple late-onset crateriform hyperkeratotic papules with a yellow color on the border of the hands and feet. A 31-year-old man presented with yellowish discrete flat-topped papules on the lateral side of his palms and fingers. The patient had a family history of similar lesions throughout three generations. The histological findings revealed hyperkeratosis with mild hypergranulosis in the epidermis, and the dermis showed no specific changes including elastorrhexis. These clinicopathologic findings were consistent with the diagnosis of FAH. Herein, we report a rare case of FAH with autosomal dominant inheritance.
