How Should Biobanks Collect Biosamples for Clinical Application? A 20-year Biomarker-related Publication and Patent Trend Analysis.
10.24171/j.phrp.2018.9.3.04
- Author:
Jae Eun LEE
1
Author Information
1. Division of Biobank for Health Sciences, Center for Genome Science, Korea National Institute of Health, Korea Centers for Disease Control and Prevention, Cheongju, Korea. eunwin21@korea.kr
- Publication Type:Original Article
- Keywords:
biomarkers;
patent;
publication;
trends
- MeSH:
Biomarkers;
DNA;
Plasma;
Publications*;
RNA;
Search Engine
- From:
Osong Public Health and Research Perspectives
2018;9(3):105-111
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: This study was designed to analyze biomarker-related publications and patent trends which biobanks could consider in planning biosample collections for biomarker research. METHODS: Publications and patents containing the term “biomarker” in the title published between 1998 to 2017 were retrieved using Scopus database and Google Patents search engine. RESULTS: Over the last 20 years there has been a steady increase in biomarker-related publications and patents; however this has slowed for patents over the last few years. Publications in 2017 that contained blood, serum, and plasma search terms in the abstract accounted for 50%, and serum as a search term in the title and abstract was more numerous than those containing blood, plasma, tissue, or urine. Blood-related patents were the most common patent in the last 10 years, and accounted for 110 patents in 2017. Biomarker-related publications since 2010 containing RNA and protein search terms in the title and abstract, were more numerous than those containing DNA and metabolite search terms. More than 27% of biomarker-related publications in 2017 and 21% of biomarker-related patents were associated with cancer. CONCLUSION: The results of this study will help biobanks establish a biosample collection strategy for clinical application.
