Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm.
- Author:
Hyun Jik LEE
1
;
Yoo Jin LEE
;
Ju Yup LEE
;
Eun Soo KIM
;
Woo Jin CHUNG
;
Byoung Kuk JANG
;
Kyung Sik PARK
;
Jae Seok HWANG
;
Kwang Bum CHO
Author Information
- Publication Type:Original Article
- Keywords: Stomach neoplasms; Endoscopic submucosal dissection; Neoplasms, second primary
- MeSH: Follow-Up Studies; Humans; Incidence; Medical Records; Methods; Neoplasms, Second Primary; Retrospective Studies; Stomach; Stomach Neoplasms*
- From:Clinical Endoscopy 2018;51(3):266-273
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) has been widely accepted as a method of treatment of early gastric tumor. This study aimed to identify the incidence and characteristics of multiple gastric tumors after ESD. METHODS: Patients with early gastric tumors who were treated by ESD from January 2004 to June 2012 and followed up with endoscopic examination periodically for at least 1 year were enrolled. All multiple gastric lesions were subsequently treated with ESD and the medical records of the patients were retrospectively reviewed. RESULTS: In total, 643 patients were included. The mean duration of endoscopic follow-up was 45.27±27.59 (range, 12–148) months. Overall, 144 patients (22.4%) showed multiple gastric tumors during the follow-up period (44 synchronous [6.8%] and 100 metachronous [15.5%]). The cumulative incidence rate steadily increased during the follow-up period. More than 50% of the tumors that developed at the same longitudinal location of the stomach were of the same macroscopic and histological type as the primary lesions. CONCLUSIONS: Because synchronous and/or metachronous gastric tumors are common, considerable attention should be paid to detect multiple gastric lesions after ESD of early gastric neoplasm.
