Progress of tumor-derived exosomal microRNA in tumors
10.3760/cma.j.issn.1006-9801.2018.05.021
- VernacularTitle:肿瘤源性外泌体微RNA在肿瘤中的研究进展
- Author:
Jie WU
1
;
Shiming WANG
Author Information
1. 山西医科大学研究生院
- Keywords:
Neoplasms;
Exosomes;
MicroRNAs
- From:
Cancer Research and Clinic
2018;30(5):358-360
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are vesicular globules with physiological functions, such as intercellular material transportation and signal transduction. They can be secreted by many kinds of cells, with 40 to 100 nm diameters.Exosomes have biological properties of derived cells based on the nucleic acids, proteins and lipids in them. Tumor cells can also secrete large number of exosomes with many microRNAs (miRNAs), and miRNAs from different maternal tumor cells are different. This paper mainly reviews the early diagnosis of tumors by tumor-derived exosomal miRNAs and the relationship between miRNAs and tumorigenesis and tumor progression.
