The application value of serological detection of ASCA and ANCA serum level in the diagnosis and treatment of inflammatory bowel disease
10.3760/cma.j.issn.1009-9158.2018.10.002
- VernacularTitle:血清学检测ASCA和ANCA在炎症性肠病诊治中的应用价值
- Author:
Yu TIAN
1
;
Huahong WANG
Author Information
1. 100034,北京大学第一医院消化内科
- Keywords:
Inflammatory bowel diseases;
Saccharomyces cerevisiae;
Antibodies;
fungal;
Antibodies;
antineutrophil cytoplasmic
- From:
Chinese Journal of Laboratory Medicine
2018;41(10):708-711
- CountryChina
- Language:Chinese
-
Abstract:
With the updating of the consensus on the diagnosis and treatment of inflammatory bowel disease, ASCA, ANCA and other serological markers are not included as routine examination items , so many related problems need to be recognized .In some special cases , the high specific serological examination still has clinical value in the differential diagnosis for atypical symptom patents .Researches support that ASCA , ANCA and other serological tests have the ability to predict the occurrence of the disease , to evaluate the biological behavior , or to predict clinical response to infliximab and the recurrence after surgery .Finding new methods for combined detection to increase sensitivity and specificity , discovery of new serological antibodies are still research hotspots in the future ."no agreement have been reached about serological detection" in the new consensus is just the expectation of large-scale, multicenter clinical research on serological detection of IBD in China .
