Radiation recall dermatitis induced by tamoxifen during adjuvant breast cancer treatment.
10.3857/roj.2014.32.4.262
- Author:
Jiyoung RHEE
;
Gwi Eon KIM
;
Chang Hyun LEE
;
Jung Mi KWON
;
Sang Hoon HAN
;
Young Suk KIM
;
Woo Kun KIM
- Publication Type:Case Report
- Keywords:
Tamoxifen;
Radiation recall dermatitis;
Treatment
- MeSH:
Breast;
Breast Neoplasms*;
Chemotherapy, Adjuvant;
Dermatitis;
Edema;
Female;
Heating;
Hot Temperature;
Humans;
Lymph Node Excision;
Middle Aged;
Radiodermatitis*;
Radiotherapy;
Receptor, Epidermal Growth Factor;
Sensation;
Tamoxifen*
- From:Radiation Oncology Journal
2014;32(4):262-265
- CountryRepublic of Korea
- Language:English
-
Abstract:
Tamoxifen and radiotherapy are used in breast cancer treatment worldwide. Radiation recall dermatitis (RRD), induced by tamoxifen, has been rarely reported. Herein, we report a RRD case induced by tamoxifen. A 47-year-old woman had a right quadrantectomy and an axillary lymph node dissection due to breast cancer. The tumor was staged pT2N0; it was hormone receptor positive, and human epidermal growth factor receptor 2 negative. The patient received adjuvant chemotherapy followed by tamoxifen and radiotherapy. After 22 months of tamoxifen, the patient developed a localized heating sensation, tenderness, edema, and redness at the irradiated area of the right breast. The symptoms improved within 1 week without treatment. Three weeks later, however, the patient developed similar symptoms in the same area of the breast. She continued tamoxifen before and during dermatitis, and symptoms resolved within 1 week.
