Electroclinical study of patients with juvenile absence epilepsy
10.3760/cma.j.issn.1006-7876.2018.09.012
- VernacularTitle:青少年失神癫痫的电-临床研究
- Author:
Wei WEI
1
;
Wenwu CHEN
;
Jinxiang WANG
;
Beibei CHEN
;
Xiaoli WANG
;
Jiang ZHU
;
Yonghong LIU
Author Information
1. 710032西安,空军军医大学西京医院神经内科,脑电监测中心;河南大学第一附属医院
- Keywords:
Epilepsy,absence;
Adolescent;
Electroencephalography;
Anticonvulsants;
Drug therapy;
Prognosis
- From:
Chinese Journal of Neurology
2018;51(9):727-731
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the electroclinical,treatment response and prognosis of juvenile absence epilepsy (JAE).Methods Thirty-two patients diagnosed as JAE from Epilepsy Center of Xijing Hospital between January 2014 and August 2017 were investigated.All of them underwent 24-hour video-electroencephalography (EEG) recording.Clinical aspects,electroencephalographic features,and antiepileptic drugs (AEPs) received were reviewed.The follow-up time was 6-44 months,with an average of (18.6 ± 11.6) months.Results Five patients (15.6％) had family history of epilepsy.Four patients (12.5％) had history of febrile seizures.Twenty-six patients (81.3％) showed absence seizures,11 patients (34.4％) were hyperventilation test positive,five patients (15.6％) were intermittent flash stimulation test positive.All the 32 patients received AEDs treatments,21 cases (65.5％) with monotherapy,nine patients (28.1％) with two AEDs,two patients (6.3％) with three AEDs.The most commonly used AED was valproic acid,and the second was levetiracetam.At the end of follow-up,five patients (15.6％) had complete seizure free and 27 patients (84.4％) had poor seizure control.Conclusions It is necessary to give electroclinical study on more samples of JAE and establish detailed practical diagnostic criteria about JAE as early as possible.More than half of JAE patients seizure control were not ideal.The monotherapy of JAE was less effective than combined treatment.
