A comparative study of comprehensive geriatric assessment in elder patients with non-Hodgkin's lymphoma
10.3760/cma.j.issn.0578-1426.2018.05.005
- VernacularTitle:老年非霍奇金淋巴瘤患者老年综合评估评分的比较研究
- Author:
Hui LIU
1
;
Ming GAO
;
Di MEI
;
Huixiu HAN
;
Jiangtao LI
;
Jiefei BAI
;
Chunli ZHANG
;
Ru FENG
;
Jianping WEI
;
Yuan TIAN
;
Ting WANG
Author Information
1. 100730,北京医院血液科
- Keywords:
Aged;
Lymphoma,non-Hodgkin;
Comprehensive geriatric assessment;
Eastern Cooperative Oncology Group (ECOG)-performance status
- From:
Chinese Journal of Internal Medicine
2018;57(5):330-334
- CountryChina
- Language:Chinese
-
Abstract:
Objective To measure the comprehensive geriatric assessment (CGA) in elder non-Hodgkin's Lymphoma (NHL) patients in a cross-sectional study;to compare the differences between Eastern Cooperative Oncology Group (ECOG)-performance status (PS) and CGA.Methods CGA stratification included the following 3 instrument assessments:activity of daily living (ADL);instrumental activity of daily living (IADL);comorbidity score according to the modified cumulative illness rating score for geriatrics (MCIRS-G).According to CGA and age,NHL patients,aged ≥60 years,were classified as "fit","unfit" and "frail" groups.ECOG-PS was evaluated and compared with CGA.Results According to CGA,51.6％ senior NHL patients (33 cases) were classified as "fit",12.5％(8 cases) as " unfit" and 35.9％ (23 cases) as "frail".Several comorbidities were observed in majority patients,such as cardiovascular disease,diabetes nellitus and hypertension.In the "younger aged" patients between 60 to 64ys,25％(3/12) was considered as "frail".However,this proportion increased to 42.9％ (6/14) in patients older than 80ys.Moreover,impaired CGA was observed in 38.9％(21/54) of ECOG-PS ≤1 patient.Conclusions Impaired CGA is as common as approximately half in elderly NHL patients and more than one third even in ECOG-PS ≤ 1 patients.ECOG-PS may underestimate the impaired fitness function in elder NHL patients.
