Efficacy of PiCCO monitoring in guiding volume therapy in patients with sepsis complicated with a-cute kidney injury
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760∕cma.j.issn.0254-1416.2018.03.027
   		
        
        	
        		- VernacularTitle:PiCCO监测指导脓毒症并发急性肾损伤患者容量治疗的效果
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Xuezhen HU
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Yuqiang GONG
			        		
			        		;
		        		
		        		
		        		
			        		Laifang SUN
			        		
			        		;
		        		
		        		
		        		
			        		Wanquan KONG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 325000,温州医科大学附属第二医院急诊 ICU
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Cardiac output;
			        		
			        		
			        		
				        		Catheterization;
			        		
			        		
			        		
				        		Swan-Ganz;
			        		
			        		
			        		
				        		Monitoring;
			        		
			        		
			        		
				        		physiologic;
			        		
			        		
			        		
				        		Sepsis;
			        		
			        		
			        		
				        		Fluid therapy;
			        		
			        		
			        		
				        		Acute kidney injury
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Anesthesiology
	            		
	            		 2018;38(3):359-362
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective To evaluate the efficacy of pulse indicator continuous cardiac output (PiC-CO) monitoring in guiding volume therapy in patients with sepsis complicated with acute kidney injury. Methods Eighty-five patients with sepsis complicated with acute kidney injury were divided into PiCCO group (n= 37) and routine group (n = 48) according to whether PiCCO monitoring was used to guide vol-ume therapy. The hemodynamic parameters at 6 and 24 h after volume therapy, fluid volume, consumption of vasoactive drugs, renal function, fatality in intensive care unit and 28-day fatality were recorded. Re-sults Compared with routine group, the volume of fluid for resuscitation at 24 h after volume therapy, and central venous pressure were significantly decreased (P<0. 05), the time of continuous renal replace-ment therapy was shortened, the urine volume was increased, the blood creatinine level was decreased, and the fatality rate in intensive care unit and 28-day fatality rate were decreased in group PiCCO (P<0. 05). Conclusion For the patients with sepsis complicated with acute kidney injury, PiCCO monitoring can reasonably guide volume therapy and is helpful in improving the prognosis.