The role of microRNAs in vascular endothelial cell aging
10.3760/cma.j.issn.0254-9026.2018.04.027
- VernacularTitle:微RNAs在血管内皮细胞衰老中的功能
- Author:
Xiao LIN
1
;
Youshuo LIU
Author Information
1. 中南大学湘雅二医院老年病科
- Keywords:
Cell aging;
MicroRNAs;
Endothelium,vascular
- From:
Chinese Journal of Geriatrics
2018;37(4):465-469
- CountryChina
- Language:Chinese
-
Abstract:
Vascular aging may influence the initiation,procession,and severity of various cardiovascular diseases,and thus is one of the most important risk factors for the high mortality of cardiovascular diseases.Vascular endothelial cells are the main cell biological basis of the vasculature,so the structure and function of vascular endothelial cells play a key role in vascular aging.Recently,the association between microRNAs and aging-related diseases has been studied.In this review,we will summarize the role of microRNAs in the process of endothelial cell aging.In addition,we will also discuss possible clinical applications of microRNAs as a diagnostic and therapeutic tool for vascular diseases.
