Association between microalbuminuria and artery elasticity in middle-aged and elderly essential hypertension patients with CHD
10.3969/j.issn.1009-0126.2018.05.009
- VernacularTitle:中老年原发性高血压伴冠心病及微量蛋白尿与动脉弹性的相关性
- Author:
Jincui XIAO
1
;
Danan LIU
;
Zhijing LI
Author Information
1. 贵州医科大学
- Keywords:
hypertension;
coronary disease;
proteinuria;
arteriosclerosis
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2018;20(5):483-486
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of microalbuminuria (MAU) on artery elasticity in middle-aged and elderly essential hypertension (EH) patients with CHD.Methods Two hundred and forty-six EH patients were divided into middle-aged EH group (n=114) and elderly EH group (n=132) with 45 EH-free subjects undergoing physical examination served as a control group.The CF-PWV,Ba-PWV and CSP in patients included in this study were measured with an arteriosclerosis detector.Results The volume of ACR and incidence of CHD were significantly higher in middle-aged and elderly EH groups than in control group (19.30％ and 16.67％ vs 0％,P＜0.05).The number of 1-,2-and 3-branch lesions was significantly greater,the ba-PWV and ACR volume were significantly higher in elderly EH group than in middle-aged EH group (P＜0.05).The number of 3-branch lesions was significantly greater,the CSP,CF-PWV,ba-PWV and ACR volume were significantly higher in middle-aged and elderly EH groups with 3-branch lesions than in those with 1-and 2-branch lesions (P＜0.05).Multivariate linear regression analysis showed that age,CF-PWV,CSP,MAU were positively associated with the number of coronary artery lesions (P＜0.05,P＜0.01).Conclusion CF-PWV and CSP can show the severity of CHD and renal damage.The renal vascular damage is exacerbated in elderly EH patients with CHD.
