Etiology of single subcortical small infarction in middle cerebral artery
10.3969/j.issn.1009-0126.2018.01.017
- VernacularTitle:大脑中动脉分布区单发皮质下小梗死患者病因分析
- Author:
Jian WANG
1
;
Yujie WANG
;
Tingting GUO
;
Biying ZHANG
Author Information
1. 辽宁省人民医院神经内科
- Keywords:
middle cerebral artery;
atherosclerosis;
leukoaraiosis;
coronary disease;
diffusion magnetic resonance imaging
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2018;20(1):67-70
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between single subcortical small infarction (SSSI) in middle cerebral artery (MCA) and large artery atheromatous sclerosis (LAAS).Methods One hundred and sixty patients with acute SSSI in MCA admitted to our hospital from January 2014 to December 2015 were divided into proximal infarction group (n=98) and distal infarction group (n=62).Their demographic,clinical,imaging data and National Institutes of Health Stroke Scale (NIHSS) score were recorded on admision.Results The incidence of coronary heart disease,NIHSS score,and contralateral intracranial artery stenosis were significantly higher while the incidence of proximal infarction,old lacunar infarction,and periventricular leukoaraiosis was significantly lower in proximal infarction group than in distal infarction group (21.4％ vs 3.2％,P=0.001;3 vs 2,P=0.030;19.4％ vs 1.6％,P=0.002;10.2％ vs 29.0％,P=0.002;16.3％ vs 33.9％,P=0.010).Logistic regression analysis showed that proximal infarction was independently related with old lacunar infarction,contralateral intracranial artery stenosis and periventricular leukoaraiosis (OR=0.270,95％CI:0.100-0.726,P=0.009;OR=4.500,95％CI:1.541-15.012,P=0.018;OR=0.325,95％CI:0.127-0.834,P=0.019).Conclusion Distal SSSI in MCA is related with small vessel disease while proximal SSSI in MCA is related with LAAS.
