The effect of microwave radiation on the permeability change of blood brain barrier
10.3760/cma.j.issn.1004-4221.2018.12.016
- VernacularTitle:微波辐射对血脑屏障通透性改变的影响
- Author:
Zhibing WU
1
;
Kan WU
;
Yajun WU
;
Shenglin MA
Author Information
1. 310006 杭州,浙江大学医学院附属杭州市第一人民医院;310002 杭州市肿瘤医院放疗科;310006 杭州,浙江省中西医结合分子肿瘤重点实验室
- Keywords:
Microwave radiation;
Blood-Brain Barrier;
Intracranial Carcinoma;
Permeability
- From:
Chinese Journal of Radiation Oncology
2018;27(12):1101-1105
- CountryChina
- Language:Chinese
-
Abstract:
Microwave radiation plays an important role in the diagnosis and treatment of malignant tumors. Whether microwave radiation can improve the effect of chemotherapy on intracranial carcinoma through improving the permeability of blood brain barrier is a hot topic at present. Blood-brain barrier permeability can be increased by microwave radiation though thermal effect and non thermal effect,and the mechanism may be related to the regulation of vascular endothelial growth factor,Occludin,aquaporin 4 and adhesion molecule-1.However, there are still questions on the physical parameters, include temperature, microwave frequency,specific absorption rate and exposure time.
