Fabrication and pre-clinical application of patient-specific 3D silicone rubber bolus for chest wall
10.3760/cma.j.issn.1004-4221.2018.09.010
- VernacularTitle:3D打印胸壁硅胶bolus制作及临床前研究
- Author:
Yanjie HOU
1
;
Jiangping YU
;
Yongqiang WANG
;
Huanru LIU
;
Da LI
;
Jingjing XU
;
Juntao ZHOU
;
Ruijuan MENG
;
Zhixin QIN
;
Xianfeng LI
Author Information
1. 山西医科大学第一医院放疗科
- Keywords:
Three-dimensional printing;
Patient-specific tissue compensator;
Silica gel;
Breast neoplasms
- From:
Chinese Journal of Radiation Oncology
2018;27(9):835-838
- CountryChina
- Language:Chinese
-
Abstract:
Objective To apply 3D printing technology to fabricate patient-specific silicone tissue compensators for the chest wall and compare the advantages and clinical characteristics between conventional bolus and 3D-printed PLA materials. Methods The chest wall data of two breast cancer patients undergoing mastectomy were obtained based upon the CT images. A patient-specific 3D printing silicone rubber bolus (3D-SRB) was designed and fabricated. The conformability of 3D-SRB,3D-PLA and conventional bolus to the chest wall were validated. Ecipse8. 6 planning system was adopted to statistically compare the dosimetric parameters of virtual plan with those after using three tissue compensators. Results The 3D-SRB was successfully designed and fabricated with a similar hardness to conventional bolus. During the process of validating conformability and radiotherapy planning,3D-SRB and 3D-PLA were superior to conventional bolus in terms of conformability to chest wall and planning dosimetric distribution.3D-SRB was advantageous in repeatability, conformability and comfortable experience compared with 3D-PLA. Regarding dosimetric parameters,3D-SRB yielded the highest repeatability with the virtual plan, followed by 3D-PLA and conventional bolus. Conclusion It is applicable to utilize 3D-SRB as the patient-specific compensators for the chest wall,which is of significance in clinical practice.
