Longitudinal layer-specific strain assessment of left ventricular systolic function of patients with coronary chronic total occlusion before and after revascularization
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1004-4477.2018.03.001
   		
        
        	
        		- VernacularTitle:分层应变评价冠状动脉慢性完全性闭塞患者血运重建前后左心室收缩功能早期改变
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Wuxu ZUO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Quan LI
			        		
			        		;
		        		
		        		
		        		
			        		Yongle CHEN
			        		
			        		;
		        		
		        		
		        		
			        		Lili DONG
			        		
			        		;
		        		
		        		
		        		
			        		Xiangfei WANG
			        		
			        		;
		        		
		        		
		        		
			        		Xianhong SHU
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 复旦大学附属中山医院 上海市影像医学研究所 上海市心血管病研究所 心超室
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Echocardiography;
			        		
			        		
			        		
				        		Coronary occlusion;
			        		
			        		
			        		
				        		Speckle tracking imaging;
			        		
			        		
			        		
				        		Ventricular function,left
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Ultrasonography
	            		
	            		 2018;27(3):185-189
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective To evaluate the longitudinal layer-specific strain of patients with coronary chronic total occlusion (CTO) before and 1 day after the percutaneous coronary intervention (PCI) by two-dimensional speckle tracking imaging (2D-STI),and then to explore the clinical value of PCI for patients with CTO. Methods A total of 30 patients diagnosed with CTO through coronary angiography and successfully taken the PCI procedure were enrolled in this study.Twenty-nine healthy volunteers were set as the control group.All patients were assigned to take echocardiography 1 day before and 1 day after PCI. The apical four-chamber (4CH),apical two-chamber (2CH) and the apical long-axis ( APLAX) echocardiographic images of all subjects were acquired.Left ventricular end-diastolic volume (LVEDV), end-systolic volume (LVESV),ejection fraction (LVEF) and stroke volume (LVSV) were measured.The mitral annular lateral S′,septal S′and average S′by tissue Doppler imaging (TDI) were also measured.The longitudinal layer-specific strain was analysed by 2D-STI.Results Compared to the control group,CTO group showed a decreased endocardial,midcardial and epicardial longitudinal strain of 4CH,2CH and APLAX ( P < 0.05). The global endocardial,midcardial and epicardial longitudinal strain were also decreased ( P <0.05).On the first day after PCI,these measures were increased compared to those on the first day before PCI (P<0.05) but the endocardial longitudinal strain of APLAX,2CH and GLS were still decreased compared to those of the control group ( P <0.05).The mitral annular lateral S′,septal S′and average S′of CTO group were decreased compared to those of the control group ( P <0.05).On the first day after PCI,the mitral annular lateral S′,septal S′and average S′were increased ( P <0.05) but showed no significant difference compared to the control group ( P > 0.05).All the other measures showed no significant difference among the three groups ( P >0.05).Conclusions The longitudinal strain of patients with CTO is decreased compared to that of healthy people and increased after PCI.