The influence of prostate volume on prostate cancer detection using real-time elastography targeted biopsy
10.3760/cma.j.issn.1004-4477.2018.01.015
- VernacularTitle:前列腺体积对实时弹性成像目标穿刺准确性的影响
- Author:
Yunkai ZHU
1
;
Yaqing CHEN
;
Jun JIANG
;
Jun QI
;
Lifeng WANG
;
Wenbin GUAN
Author Information
1. 200092,上海交通大学医学院附属新华医院超声科
- Keywords:
Elasticity imaging techniques;
Prostatic neoplasms;
Biopsy
- From:
Chinese Journal of Ultrasonography
2018;27(1):64-68
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively evaluate the influence of prostate volume on prostate cancer detection using elastography targeted transperineal biopsy. Methods A total of 573 consecutive patients suspicious for prostate cancer were enrolled in this study. Patients underwent combined elastography-targeted biopsy and 10 core-systematic transperineal biopsy.In correlation with prostate biopsy pathology, the sensitivity of elastography-targeted biopsy and systematic biopsy were compared among four subgroups with different prostate volume.Results The overall prostate cancer detection rate was 42.9% (246/573). The increase in cancer detection rate by elastography-targeted biopsies was 9.1% (52/573).In patients with prostate volume of ≤30 ml,30-50 ml,50 -80 ml and >80 ml,the sensitivity of elastography targeted biopsy were 91.1% (72/79),81.3% (87/107),70.5% (31/44) and 50.0% (8/16),respectively ( P =0.000).The sensitivity of systematic biopsy were 77.2% (61/79),77.6% (83/107),86.4% (38/44) and 75.0% (12/16),respectively,in comparison among these four groups ( P = 0.601). For patients with prostate volume ≤30 ml,the sensitivity of elastography targeted biopsy was significantly higher than that of systematic biopsy (P= 0.028). Conclusions Prostate cancer detection rate can be improved by elastography targeted biopsy. Prostate volume is correlated with the accuracy of elastography. The sensitivity of elastography targeted biopsy is higher in patients with a smaller prostate gland.
