The study of nicotine addiction abstinence in patients with insular infarction
10.3760/cma.j.issn.1674-6554.2018.11.004
- VernacularTitle:岛叶梗死患者尼古丁成瘾戒断研究
- Author:
Pingping SU
1
;
Youling ZHU
;
Chunhua XI
;
Kai WANG
Author Information
1. 安徽医科大学第三附属医院(合肥市第一人民医院)神经内科
- Keywords:
Insular infarction;
Nicotine;
Addiction;
Abstinence
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2018;27(11):976-980
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of insular on the addiction of nicotine after insular infarction. Methods Totally 35 patients with lesions involving insular infarction were enrolled in insular damage group. The patients matched with the demographic data of the study subjects who did not involve in-sular infarction were the control group(n=114). All patients were given the internationally popular question-naire of smoking urges ( QSU) and fagerstrom test for nicotine dependence( FTND) during hospitalization, and they were followed up 3 months after stroke. The QSU and the minnesota nicotine withdrawal scale ( MNWS) were assessment for patients who did not smoke again and did not relapse,and the QSU and FTND scale were used for the patients who still smoke. Results After 3 months follow-up,the rate of withdrawal from insular damage was 77. 14%,and that in non-insular damage was 52. 63%(χ2=6. 62,P=0. 01),and the MNWS in two groups(insular damage patients (0. 59±0. 97) and non-insular damage patients(1. 15± 1. 29)),the difference was statistically significant (t=-2. 00,P=0. 04). All subjects were evaluated by questionnaire of smoking urges (QSU),among which QSU score was (19. 40±9. 63) in insular damage group and (24. 47±10. 39) in non-insular group,the difference was statistically significant (t=-2. 57,P=0. 01) . Conclusion Patients with insular lesion are more likely to cause withdrawal of nicotine addiction, suggesting that insular may be involved in cognitive processing of addiction.
