Effects of gastric residual volume set at different thresholds on intensive care patients receiving enteral nutrition: a systematic review
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1674-635X.2018.01.002
   		
        
        	
        		- VernacularTitle:不同胃残留量阈值设置对ICU行肠内营养患者影响的系统评价
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Song ZHOU
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Jianning WANG
			        		
			        		;
		        		
		        		
		        		
			        		Mengmei ZHAN
			        		
			        		;
		        		
		        		
		        		
			        		Qiuxia HUANG
			        		
			        		;
		        		
		        		
		        		
			        		Liling ZHA
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 330006,南昌大学第一附属医院护理部
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Enteral nutrition;
			        		
			        		
			        		
				        		Intensive care units;
			        		
			        		
			        		
				        		Meta-analysis;
			        		
			        		
			        		
				        		Gastric residual volume;
			        		
			        		
			        		
				        		Complications
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Clinical Nutrition
	            		
	            		 2018;26(1):9-16
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective To compare the effects of gastric residual volume (GRV) set at different thresholds on intensive care patients receiving enteral nutrition (EN),so as to inform clinical practice.Methods Controlled clinical trials involving different GRV thresholds in ICU patients undergoing EN were retrieved from multiple electronic databases (including Cochrane Library,PubMed,Ovid Medline,Web of Science,CBM,CNKI,Wanfang Data,and VIP).Quality of the retrieved studies was evaluated for data extraction,and meta-analysis was performed.Results Four randomized controlled trials and one clinically controlled trial were included in the study,with a total of 658 subjects.Results of the meta-analysis suggested no statistically significant difference between the group with GRV threshold≥250 ml and the one with GRV threshold<250 ml in the rates of pneumonia (OR =1.19,95% CI =0.77-1.82,P =0.43),aspiration.(OR =1.59,95% CI =0.42-6.03,P=0.50),vomiting (OR=1.35,95% CI=0.48-3.80,P=0.57),reflux (OR=1.29,95% CI=0.58-2.88,P=0.53),and diarrhea (OR=1.36,95% CI=0.87-2.13,P=0.17).Nutrient intake and several other outcome measures were unable to be included in the meta-analysis for either the scarcity of studies or inconsistency in the measures adopted,and descriptive analysis was therefore employed instead.Conclusion There was no significant difference between the two groups in terms of complications,but the group with GRV threshold≥250 ml had higher intake of EN.