Antibacterial effect of anti-tuberculosis decoction against clinical isolated mycobacterium tuberculosis in vitro
10.3760/cma.j.issn.1008-6706.2018.01.025
- VernacularTitle:抗痨合剂对临床分离结核分枝杆菌体外抑菌作用的研究
- Author:
Jing GUO
1
;
Zhongda LIU
;
Zunjing ZHANG
Author Information
1. 丽水市中医院感染科
- Keywords:
Anti-Tuberculosis decoction;
Rifampicin;
Mycobacterium tuberculosis;
Antibacterial
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(1):96-98
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the antibacterial activity of anti-tuberculosis decoction against clinical isolated rifampicin drug-resistant mycobacterium tuberculosis (number:A) and rifampicin sensitive mycobacterium tuberculosis (number:B) in vitro.Methods Rifampicin was selected as a positive control medicine.Anti-tuberculosis decoction and rifampicin were respectively used to test the bacteria through absolute concentration method and the direct effect method,then recorded and analyzed the observation phenomenon.Results The MIC of anti-tuberculosis decoction for A,B was 64.00mg/mL by using the absolute concentration method,and the MIC of anti-tuberculosis decoction for A,B was 8.00mg/mL by using direct effect method.Conclusion Anti-tuberculosis decoction had a good antibacterial activity for rifampicin resistant mycobacterium tuberculosis and rifampicin sensitive mycobacterium tuberculosis in vitro.
