Exercise intervention improves motor symptoms of Parkinson disease and underlying mechanisms
10.3969/j.issn.1000-4718.2018.04.027
- VernacularTitle:运动干预改善帕金森病运动症状及可能机制的研究进展
- Author:
Ping CHEN
1
;
De-Cai QIAO
;
Xiao-Li LIU
Author Information
1. 北京师范大学体育与运动学院
- Keywords:
Exercise intervention;
Parkinson disease;
Motor symptoms
- From:
Chinese Journal of Pathophysiology
2018;34(4):745-753
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson disease(PD)is one of the most common neurodegenerative diseases in the world.Many PD treatment programs are designed to manage motor symptoms by drug or surgical intervention(such as deep brain stimu-lation).Although these regimens improve the symptoms of PD or slow the development of the disease,certain side effects remain unsolved during the treartment,and lack of neuroprotective strategies is still the main problem.Exercise or physical exercise can reduce the risk of PD,and significantly improve the movement symptoms of PD or slow down the development of the disease through different neurobiological mechanisms.This article intends to review the progress in improving the movement symptoms of PD and the possible mechanism of exercise intervention for PD.
