Value of thromboelastography in predicting thromboembolic complications in patients with intracranial an-eurysms after stent-assisted coiling
10.16571/j.cnki.1008-8199.2018.03.007
- VernacularTitle:血栓弹力图对预测颅内动脉瘤支架辅助栓塞术血栓相关并发症的作用
- Author:
Bin WANG
1
;
Shao-Xian WANG
;
Xing-Long LIU
;
Chun ZHOU
;
Lin-Bo ZHAO
;
Yue-Zhou CAO
;
Sheng LIU
Author Information
1. 南京医科大学第一附属医院(江苏省人民医院)介入放射科
- Keywords:
thromboelastography;
intracranial aneurysm;
stent;
complication
- From:
Journal of Medical Postgraduates
2018;31(3):254-257
- CountryChina
- Language:Chinese
-
Abstract:
Objective Few researches have been reported about thromboelastography(TEG)in detecting the complications after stent-assisted coiling for intracranial aneurysms. This study aimed to investigate the value of TEG in predicting thromboembolic complications in patients with intracranial aneurysms after stent-assisted coiling. Methods We retrospectively analyzed the clinical data on 152 cases of intracranial aneurysms undergoing stent-assisted coiling in our department,18 with and 134 without thrombosis. We assessed the effects of antiplatelet drugs by TEG,recorded the general data and postoperative complications,and identified the po-tential risk factors for thromboembolic complications by multivariate logistic regression analysis. Results The incidence rate of aspi-rin resistance was significantly lower than that of clopidogrel resistance(10.5% vs 30.3%,P<0.05). Thromboembolic complications were observed in 18 patients during the perioperative and follow-up periods. Multivariate logistic regression analysis showed that the in-dependent risk factors for thromboembolic complications were the maximum amplitude of TEG(OR=1.152,95% CI:1.002-1.300, P=0.021)and aspirin resistance(OR=4.945,95% CI:1.408-17.375,P=0.013). Conclusion TEG is effective in evaluating the effects of antiplatelet drugs in patients with intracranial aneurysms undergoing stent-assisted coiling. Elevated maximum amplitude of TEG and aspirin resistance may increase the risk of thromboembolic complications.
