Study of brain perfusion with IVIM-DWI in early hypertension
10.7687/j.issn1003-8868.2018.04.064
- VernacularTitle:IVIM-DWI技术在早期高血压患者脑灌注中的应用研究
- Author:
Lang-Lang GAO
1
;
Yu-Feng LIU
;
Shan-Shan CHEN
;
Hai-Tao LIU
;
Fang DU
;
Wei-Huan HOU
;
Shun QI
;
Hai-Tao ZHAO
;
Meng-Qi WEI
Author Information
1. 空军军医大学第一附属医院放射科
- Keywords:
IVIM-DWI;
hypertensive encephalopathy;
MRI;
perfusion-related diffusion coefficient;
perfusion fraction
- From:
Chinese Medical Equipment Journal
2018;39(4):64-66,82
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of intra-voxel incoherent motion diffusion weighted imaging(IVIM-DWI)in brain perfusion of early hypertensive patients. Methods Totally 36 hypertensive patients and 14 volunteers were recruited and scanned using routine MRI sequences including axial T2WI, T1WI, T2FLAIR, TOF-MRA and IVIM-DWI sequence. Perfusion-related diffusion coefficient (D*) values and perfusion fraction (f) values in various regions were measured separately.The independent sample t test was used to analyze the data.Results Compared with the volunteers,both D*values and f values in lenticular nucleus,thalamus,superior frontal gyrus,occipital lobe,genu of corpus callosum(CC)and posterior horns of periventricular WM, were found to be lower (P<0.05) in hypertensive patients. For other regions, there were no significant difference(P>0.05).Conclusion IVIM-DWI has the ability to detect subtle brain perfusion abnormalities at early stages of hypertension.It has an important value to the prevention and treatment of hypertensive encephalopathy.
