Analysis of the serological testing results from Aier Eye Bank
10.3760/cma.j.issn.2095-0160.2018.05.006
- VernacularTitle:爱尔眼库角膜供体血清学检测结果分析
- Author:
Wenxiu LONG
1
;
Lihong YANG
;
Jie XU
;
Shengyu HE
;
Shaowei LI
;
Congxiang WANG
;
Kehua WANG
;
Ruqiu RAN
;
Jian TANG
Author Information
1. 中南大学爱尔眼科学院
- Keywords:
Corneal donors;
Serological testing;
Hepatitis B virus surface antigen;
Safety
- From:
Chinese Journal of Experimental Ophthalmology
2018;36(5):351-354
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study was to evaluate the safety of 640 corneal donors by analysing the serological testing results.Methods We retrospectively analyzed the serological testing results from Changsha Aier Eye Bank and Chengdu Kangqiao Aier Eye Bank from January 2011 to December 2015,hepatitis B virus surface antigen (HBsAg),hepatitis C virus (HCV),treponema pallidum (TP) and human immunodeficiency virus (HIV) were detected by colloidal gold or enzyme-linked immunosorbent assay (ELISA).Results There were 83 out of 640 serum samples showed positive immuno-reaction assayed markers,the positive rate was 12.97％,including HBsAg(n=60,9.38％),HCV(n=3,0.47％),TP(n=11,1.72％) and HIV(n=2,0.31％).Moreover,3 corneal donors were both positive against HBsAg and HCV,2 donors positive against HCV and TP,1 donor positive against HBsAg and HIV,1 donor positive against HBsAg and TP.Conclusions There is a high proportion of positive results of blood-borne diseases in cornea donors,which is a potential threat to corneal receptors and eye bank workers.Therefore,it is very important to detect serological test strictly for corneal donors.
