Investigation on the clinical application of blood purification in PICU
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1673-4912.2018.10.003
   		
        
        	
        		- VernacularTitle:血液净化治疗在PICU的临床应用调查
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Lijie WANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xihan CHE
			        		
			        		;
		        		
		        		
		        		
			        		Wenhe GUAN
			        		
			        		;
		        		
		        		
		        		
			        		Jia YANG
			        		
			        		;
		        		
		        		
		        		
			        		Fan ZHAO
			        		
			        		;
		        		
		        		
		        		
			        		Nan LI
			        		
			        		;
		        		
		        		
		        		
			        		Linxi HE
			        		
			        		;
		        		
		        		
		        		
			        		Yiming WANG
			        		
			        		;
		        		
		        		
		        		
			        		Wei XU
			        		
			        		;
		        		
		        		
		        		
			        		Chunfeng LIU
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 中国医科大学附属盛京医院PICU
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Blood purification;
			        		
			        		
			        		
				        		Indication;
			        		
			        		
			        		
				        		Children;
			        		
			        		
			        		
				        		Critical
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Pediatric Emergency Medicine
	            		
	            		 2018;25(10):729-732,740
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To investigate the development and application of blood purification in PICU. Methods The demographic data,diagnosis,length of stay,prognosis,patterns and frequency of blood purifi-cation and complications of PICU patients treated with blood purification in our hospital from 2010 to 2017 were retrospectively analyzed. Results The patients with blood purification accounted for 3. 1% of hospital-ized children in the same period. From 2010 to 2017,the patients and times with blood purification increased by 370. 6% and 398. 3% respectively. The times of continuous veno-venous hemodiafiltration(CVVHDF), plasma exchange and hemoperfusion increased by 135. 2%,6300% and 1600% respectively. The frequency of CVVHDF,plasma exchange and hemoperfusion accounted for 42. 8%(492/1151),33. 5%(386/1151), and 23. 7% (273/1151) respectively. Drug and toxic poision accounted for the highest proportion of 28. 6%(81/284),neurological diseases accounted for 20. 8%(59/284),sepsis with multiple organ dysfunction syn-drome accounted for 18. 0%( 51/284 ) , digestive system diseases, autoimmune diseases, renal diseases and metabolic diseases accounted for 14. 4%( 41/284 ) ,4. 9%( 14/284 ) ,4. 9% ( 14/284 ) and 4. 2%( 12/284 ) respectively. The cure rate was 63. 8%. Complication included thrombus. Conclusion Blood purification has become the preferred modality for the management of critically ill children. Pediatric blood purification tech-niques have developed rapidly in our PICU and domestic pediatric. Further specification is required,so that it may represent the adequate choice for critical ill children.