Application of Vitamin E in Pregnant Women with Autoimmune Thyroid Disease

VernacularTitle:维生素E在自身免疫性甲状腺疾病孕妇中的临床应用
Author: Chijia ZENG ¹ ; He HU ; Weiling LIU ; Weiqi LIU ; Yuhua LIU
Author Information

1. 佛山市禅城区中心医院广东佛山 528000
Keywords: Autoimmune Thyroid Disease; Pregnant Women; Vitamin E; Adverse Pregnancy
From: Modern Hospital 2018;18(5):722-724
CountryChina
Language:Chinese
Abstract: Objective To investigate the changes of serum vitamin E in pregnant women with autoimmune thyroid diseases and provide evidence for clinical prevention of adverse pregnancy caused by oxidative stress. Methods Randomly selecting 221 cases of obstetrics and gynecology pregnant women in outpatient clinics in Chancheng District Central Hospital. A double antibody one-step sandwich enzyme-linked immunosorbent assay (ELISA) was used to detect vitamin E concentration. Results The results of 221 subjects were normally distributed. The vitamin E concentration in the disease group was (353. 93 ± 141. 28) mmol/L, and the control group was (310. 49 ± 105. 49) mmol/L. There was a significant difference between the two groups (P＜0. 05). The concentration of vitamin E in different gestational weeks gradually decreased with the increase of pregnancy, and the difference between them was statistically significant (F = 8. 417, P＜0. 05). Conclusion The presence of oxidative stress during pregnancy in women with autoimmune thyroid diseases should be valued by clinicians.