Correlation between RoPE score and right-to-left shunt severity in patients with cryptogenic stroke
10.7652/jdyxb201802023
- VernacularTitle:隐源性脑梗死患者反常性栓塞量表评分与右向左分流严重程度的关系
- Author:
Jiao-Jiao MA
1
;
Ni-Na ZHAI
;
Liu YANG
;
Wen-Li ZHANG
;
Gui-Lian ZHANG
;
Hai-Qin WU
;
Shu-Qin ZHAN
;
Ning BU
Author Information
1. 西安交通大学第二附属医院神经内科
- Keywords:
right-to-left shunt;
patent foramen ovale;
cryptogenic stroke;
contrast-enhanced transcranial doppler;
contrast-enhanced transthoracic echocardiography
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2018;39(2):271-275
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical features between cryptogenic stoke(CS)with and without right-to-left shunt(RLS)so as to determine whether shunt severity determined by control-enhanced transcranial Doppler(c-TCD)is correlated with the risk of paradoxical embolism(RoPE)score.Methods We made a retrospective analysis of clinical characteristics of 138 CS patients with and without RLS admitted to our department between January 2014 and November 2016.For patients documented by c-TCD,we evaluated whether there was a correlation between RLS severity and RoPE score. RLS was diagnosed by c-TCD and contrast-enhanced transthoracic echocardiography(c-TTE).We compared every modality for detecting RLS with and without Valsalva maneuver.For patients found with RLS in c-TCD and c-TTE,we judged whether there was an agreement in grading RLS between two modalities.Results For patients with CS,shunt severity by c-TCD was positively correlated with RoPE score(r= 0.26,P= 0.05).The clinical features were different between CS patients with RLS and without RLS.Compared with the positive results of c-TCD and c-TTE at rest,the positive rate was higher in Valsalva maneuver,respectively(P＜0.01).There was a moderate agreement between shunt grades identified by the two techniques(Kappa=0.428).Conclusion There is a positive correlation between RoPE score and RLS severity determined by c-TCD in CS patients.Valsalva maneuver can significantly increase the positive rate of RLS detected by c-TCD and c-TTE.
