Diagnosis and Treatment of Primary Duodenal Adenocarcinoma
	    		
		   		
		   			
		   		
	    	
    	 
    	10. 3969/j. issn. 1008-7125. 2018. 06. 011
   		
        
        	
        		- VernacularTitle:原发性十二指肠腺癌诊治进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yuxue SHI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Weichang CHEN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 苏州大学附属第一医院消化科 215000
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Duodenal Neoplasms;
			        		
			        		
			        		
				        		Diagnosis;
			        		
			        		
			        		
				        		Therapy;
			        		
			        		
			        		
				        		Prognosis
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Gastroenterology
	            		
	            		 2018;23(6):370-373
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Primary duodenal adenocarcinoma (PDA)is a rare but aggressive digestive tract malignancy,and its incidence is increasing in recent years. Early diagnosis of PDA is challenging due to nonspecific symptoms. Hence,it is often detected at an advanced stage. Treatment strategies tends to favor aggressive surgical resection. Adjuvant chemotherapy and radiation are important components of multi-modality treatment for patients with high risk of recurrence, and molecular targeted therapy is still in the exploratory stage. The best adjuvant therapy after operation is not yet clear. Early diagnosis and treatment is of great significance for prognosis. This article reviewed advances in epidemiology,risk factors,diagnosis,treatment and prognosis of PDA.