Clinical Analysis of Inpatients With Inflammatory Bowel Disease in Last Decade(2008-2017)
10.3969/j.issn.1008-7125.2018.04.003
- VernacularTitle:2008-2017年炎症性肠病住院患者临床变迁分析
- Author:
Ting LI
1
;
Qiaomin WANG
Author Information
1. 安徽医科大学附属省立医院消化内科 230001
- Keywords:
Colitis,Ulcerative;
Crohn Disease;
Inflammatory Bowel Disease;
Diagnosis;
Therapy
- From:
Chinese Journal of Gastroenterology
2018;23(4):204-208
- CountryChina
- Language:Chinese
-
Abstract:
Background:The clinical characteristics and management approaches of inflammatory bowel disease(IBD)change accordingly with the increasing incidence of the disease. Aims:To investigate the clinical changes of IBD in the last decade(2008-2017)in Anhui Provincial Hospital. Methods:Hospitalization data of patients with newly diagnosed IBD admitted from Jan. 2008 to Nov. 2017 at the Anhui Provincial Hospital were collected,and then the clinical characteristics and management approaches were compared between Group A(2008-2012)and Group B(2013-2017). Results:A total of 515 IBD cases were enrolled in this study. Hospitalized IBD cases increased significantly from 2013 to 2017. Cases of ulcerative colitis(UC)was 3.72 times and cases of Crohn's disease(CD)was 3 times in 2017 as that in 2013. In Group A,UC mainly involved the left colon(47.8%),with mild-to-moderate activity(85.3%);while the majority of UC in Group B presented as pancolitis(54.5%),and mostly with moderate-to-severe disease(83.8%). In group B,the proportion of CD involving ileocolon(65.5%)and with moderate-to-severe disease(58.6%)was significantly increased;complications occurred in 50.9% of the CD patients,predominantly the perianal lesions(44.8%). In the past 5 years, colonoscopy and biopsied pathology were more accessible(>95%),and the detection rate of typical pathological changes, as well as the comprehensive diagnosis based on clinical,colonoscopic and pathological findings were significantly increased. In respect of treatment modalities,steroids and immunosuppressants were more frequently used in UC,and immunosuppressants,biological agents and enteral nutrition were more frequently used in CD in the past 5 years. Conclusions:The number of hospitalized IBD patients admitted in Anhui Provincial Hospital increased significantly in the past 5 years. The clinical characteristics and management approaches of IBD changed as time passed. The diagnosis and treatment were significantly improved.
