Value of clearance rate of sTREM-1c in assessing prognosis in patients with septic shock
10.3969/j.issn.1006-5725.2018.01.016
- VernacularTitle:可溶性髓样细胞触发性受体-1清除率评估脓毒症休克患者预后的价值
- Author:
Yunshan LUO
1
;
Yilin LIU
;
Xiamei DENG
;
Jian ZHANG
;
Li LI
;
Mingqing RAO
;
Jianling LUO
Author Information
1. 粤北人民医院重症医学科
- Keywords:
soluble myeloid cell triggering receptor;
soluble myeloid cell triggered receptor clearance;
septic shock;
acute physiology and chronic health scoring system Ⅱ;
prognosis
- From:
The Journal of Practical Medicine
2018;34(1):67-70
- CountryChina
- Language:Chinese
-
Abstract:
Objective To monitor the dynamic change of soluble myeloid cells trigger receptor 1 (sTREM-1)and the clearance rate of sTREM-1 (sTREM-1 c) in patients with sepsis shock and to explore its value in assessing the prognosis.Methods A total of 54 patients from January to December 2016 were divided into improved group and death group,sTREM-1 and sTREM-1c level at 1,5,7 and 9 d were monitored and the receiver-operating characteristic curve analysis was used to judge its value in prognosis.Results Comparison of baseline of APACHE Ⅱ score,PCT and age in 2 groups was statistically significant.After treatment,the sTREM-1 level declined,especially in improved group.Similarly,sTREM-1c in improved group at 5,7 and 9 d dropped more significantly than that in death group (P ＜ 0.05).At different time points,sTREM-1 7 topped the predictive value of AUC on the prognosis,followed by APACHE Ⅱ and sTREM-1 5,PCT,sTREM-1 9,sTREM-1c 9 and sTREM-1 1,and sTREM-1c 5 and sTREM-1c 7 were the minimum.Conclusion Effect of dynamic monitoring of sTREM-1 and sTREM-1c analysis in clinic is better than that of simply monitoring of sTREM-1.
