The application value of liver volume measurement and Gd-EOB-DTPA enhanced MRI to evaluate hepatic reserve function
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1002-1671.2018.04.015
   		
        
        	
        		- VernacularTitle:Gd-EOB-DTPA增强MRI与肝脏体积评估肝储备功能的应用价值
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Xun LI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xinguan YANG
			        		
			        		;
		        		
		        		
		        		
			        		Yu JIANG
			        		
			        		;
		        		
		        		
		        		
			        		Weijia QIU
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 桂林医学院附属医院放射科
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		magnetic resonance imaging;
			        		
			        		
			        		
				        		Gd-EOB-DTPA;
			        		
			        		
			        		
				        		liver volume measurement;
			        		
			        		
			        		
				        		hepatic reserve function
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Practical Radiology
	            		
	            		 2018;34(4):545-548
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To probe the value of both liver volume(LV)measurement and Gd-EOB-DTPA enhanced MRI to evaluate hepatic reserve function in order to obtain a better assessment method.Methods Clinical and imaging data of 42 patients with hepatic focal lesions were analyzed retrospectively.Gd-EOB-DTPA enhanced MRI scan,Child-Pugh scoring and ICG clearance tests were performed in all patients,and the liver relative enhancement (RE)and LV were used to assess the hepatic reserve function.The differences of LV, LV/standard liver volume (SLV)and RE between the Child-Pugh class A and B were compared using independent student's t-test. Spearman correlation analysis was applied to analyze the relationship of indocyanine green retention rate at 1 5 minutes (ICG-R1 5) with the LV,LV/SLV,RE,RE×LV and RE×LV/SLV.Results There was no significant difference in LV between two groups(P>0.05), whereas the RE had significant difference(P=0.039).There were no significant correlations between ICG-R15 and LV,LV/SLV(P>0.05). ICG-R1 5 was negatively correlated with RE,RE×LV and RE×LV/SLV,and RE×LV/SLV showed significant correlation with ICG-R15 (r=-0.524,P=0.000).Conclusion Gd-EOB-DTPA enhanced MRI can assess the status of hepatic reserve function, while the combination of RE with LV is a more effective method.