Role of cell death mechanism in viral myocarditis
10.3760/cma.j.issn.2095-428X.2018.01.005
- VernacularTitle:病毒性心肌炎与细胞死亡机制
- Author:
Yujie QIAN
1
;
Zuocheng YANG
Author Information
1. 中南大学湘雅三医院儿科
- Keywords:
Viral myocarditis;
Apoptosis;
Autophagy;
Necrosis
- From:
Chinese Journal of Applied Clinical Pediatrics
2018;33(1):18-20
- CountryChina
- Language:Chinese
-
Abstract:
Viral myocarditis is a nonspecific myocardial inflammation caused by viral infection,10％ - 20％ of them can develop to dilated cardiomyopathy eventually. Virus infections caused direct myocardial damage as they at-tack. Persistent inflammation and persistent virus infections induced an immune inflammation response and eventually caused indirectly damage,leading to further harm to myocardia. Different forms of cell death including apoptosis,autoph-agy,necrosis and necroptosis were associated with myocarditis. The role and mechanism of different cell death in the development of viral myocarditis will be described.
