Progression of studies on virulence factors and pathogenesis of Bordetella pertussis
10.3760/cma.j.issn.2095-428X.2017.22.003
- VernacularTitle:百日咳鲍特菌的毒力因子及其致病机制研究进展
- Author:
Qinghong MENG
1
;
Wei SHI
;
Kaihu YAO
Author Information
1. 100045 国家儿童医学中心,首都医科大学附属北京儿童医院,北京市儿科研究所,儿科学国家重点学科,国家呼吸系统疾病临床医学研究中心,教育部儿科重大疾病研究重点实验室,儿童呼吸道感染性疾病研究北京市重点实验室
- Keywords:
Pertussis;
Virulence factors;
Pathogenesis;
Immune suppression
- From:
Chinese Journal of Applied Clinical Pediatrics
2017;32(22):1688-1691
- CountryChina
- Language:Chinese
-
Abstract:
In 1906,it was confirmed that the pertussis was caused by Bordetella pertussis (BP).Virulence factors of BP had been studied widely for over a hundred years,however,the pertussis pathology remains largely unknown.The development of a baboon model will promote the study of the pathogenesis of BP infection and disease,and the understanding about the pathogenesis is helpful for the prevention and therapeutics of pertussis.
