Premarketing Clinical Evaluation of Drug-induced Liver Injury
- VernacularTitle:上市前药物引起肝损伤的临床评估
- Author:
Na AN
1
;
Jianyuan TANG
;
Ruyi HE
Author Information
- Keywords: Drug-induced liver injury; Hy's law; clinical evaluation; hepatotoxic.ity; new drug
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(6):931-935
- CountryChina
- Language:Chinese
- Abstract: The liver injury caused by drug and / or its metabolites is one of the most common reasons for drugs to be withdrawn or disapproved.Premarketing clinical evaluation of drug-induced liver injury (DILI) is extremely important to drug evaluation.Signals of DILI and Hyman's Law (Hy's Law),clinical evaluation and lessons of DILI were discussed to help developing new drugs.
