Influence of menopause status on breast fibrograndular tissue and background parenchymal enhancement
10.3969/j.issn.1672-8467.2018.02.003
- VernacularTitle:月经状态对乳腺纤维腺体组织与背景实质强化的影响
- Author:
Xiao-Xin HU
1
;
Ya-Jia GU
;
Luan JIANG
;
Qiang LI
;
Chao YOU
;
Jian MAO
;
Wei-Jun PENG
Author Information
1. 复旦大学附属肿瘤医院放射诊断科 上海200032;复旦大学上海医学院肿瘤学系 上海200032
- Keywords:
breast;
fibrograndular tissue;
background parenchymal enhancement;
menopause status;
quantitative assessment
- From:
Fudan University Journal of Medical Sciences
2018;45(2):158-163
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the influence of menopause status on breast fibrograndular tissue (FGT),background parenchymal enhancement volume ratio (BPEv) and intensity ratio (BPEI) by breast MR image automatic quantitative analysis.Methods From 14 033 consecutive patients who underwent breast MR in our center from 2009 to 2012,we randomly selected 101 normal cases (47cases of premenopausal and 54 cases of postmenopausal).Premenopausal status was subclassified into four groups (8 cases in the 1st week and 13 cases in the 2nd,3rd and 4th week,respectively) based on the menstrual cycle.We evaluated FGT,BPEv and BPEI at early (2 minutes),medium (4 minutes) and late (6 minutes) enhanced time phases of breast MRI for quantitative assessment.The FGT,BPEv and BPEI in premenopausal and postmenopausal women were compared using the Mann-Whitney U test.Comparison of each menstrual cycle was made using the Kruskal-Wallis test.Results The FGT,BPEv and middle-late BPEI of postmenopausal women were significantly lower than that of premenopausal women (P＜0.05).The maximum BPEI was in the 1st week,the minimum in the 2nd week in premenopausal women (P＜0.05).The FGT and BPEv in the 1st week were the highest among the 4 weeks,but there was no significant difference.Conclusions The FGT,BPEv and BPEI were significantly decreased after menopause.The optimal time of breast MR examination is in the 2nd week of menstrual cycle.
