Research advances in polymorphisms of pancreatitis-associated genes
10.3969/j.issn.1001-5256.2018.03.051
- VernacularTitle:胰腺炎相关基因多态性的研究进展
- Author:
Yanbing ZHANG
1
;
Youming DING
Author Information
1. 武汉大学人民医院肝胆腔镜外科
- Keywords:
pancreatitis;
polymorphism,single nucleotide;
review
- From:
Journal of Clinical Hepatology
2018;34(3):667-671
- CountryChina
- Language:Chinese
-
Abstract:
Mutations and polymorphisms of genes associated with pancreatic function are involved in the development and progression of pan-creatitis. In addition,systemic inflammatory response also affects the severity of pancreatitis,while mutations and polymorphisms of genes which encode inflammatory factors and cytokines can regulate the expression of such factors and thus affect the progression of systemic inflam-matory response. This article reviews the association between pancreatitis and polymorphisms of genes related to cationic trypsinogen,pancre-atic secretory trypsin inhibitor,cystic fibrosis conductance regulator,inflammatory factors,and cytokines.
