Research advances in serum markers and transient elastography in the evaluation of liver fibrosis
10.3969/j.issn.1001-5256.2018.03.040
- VernacularTitle:血清标志物与瞬时弹性成像技术评估肝纤维化的研究进展
- Author:
Fengming XU
1
;
Qingshou SHENG
Author Information
1. 广西中医药大学
- Keywords:
liver cirrhosis;
elasticity imaging techniques;
biological markers;
diagnosis;
review
- From:
Journal of Clinical Hepatology
2018;34(3):618-622
- CountryChina
- Language:Chinese
-
Abstract:
Studies have shown that liver fibrosis and some cases of early liver cirrhosis can be reversed,and thus a timely,accurate judg-ment of fibrosis degree has important clinical significance in prevention/treatment and prognostic evaluation of chronic liver diseases. In re-cent years,great achievements have been made in the application of serum markers and transient elastography for the evaluation of liver fibro-sis. This article introduces the value of serological markers and related models in evaluating liver fibrosis,including CHI3L1,GP model, Forns,APRI,and FIB-4 index,and reviews the advances in the application of transient elastography in determining fibrosis stage in pa-tients with chronic liver diseases. It is pointed out that a combination of these two methods has a high value in evaluating fibrosis degree.
