Host contributions to Ebola virus replication, transcription and translation:research advances
10.7644/j.issn.1674-9960.2017.11.015
- VernacularTitle:埃博拉病毒复制、转录和翻译过程中宿主互作因子的研究进展
- Author:
Zhong-Yi WANG
1
;
Ying-Ying FU
;
Jia-Ming LI
;
Zhen-Dong GUO
;
Zong-Zheng ZHAO
;
Chun-Mao ZHANG
;
Jun QIAN
;
Lin-Na LIU
Author Information
1. 军事科学院军事医学研究院
- Keywords:
Ebola virus;
replication;
transcription;
translation;
host;
interaction
- From:
Military Medical Sciences
2017;41(11):938-941
- CountryChina
- Language:Chinese
-
Abstract:
Ebola virus(EBOV) disease,the fatality rate of which is as high as 25％-90％,can be transmitted by contac t between human and non-human primates.Early studies of the virus focused on the functions of viral proteins.Recently,the focus of research of EBOV has been switched to the host interaction factors during the process of virus reproduction.In this review,advances in studies on host contributions to EBOV replication,transcription and translation are summarized in order to enhance our understanding of contributions of the host to the virus reproduction process and provide reference for research strategies and new antiviral drugs.
