Qualitative and quantitative study of Shengui anti-pruritic mixture
10.3760/cma.j.issn.1673-4246.2018.03.014
- VernacularTitle:参归止痒合剂定性定量研究
- Author:
Wei GONG
1
;
Xu SUN
;
Kun ZHANG
;
Zhenxing ZHANG
;
Xinxin ZHANG
;
Yuping ZHOU
;
Zheng WANG
;
Yingchun SONG
Author Information
1. 250022,济南军区联勤部药品仪器检验所
- Keywords:
Chromatography,thin layer;
Chromatography,high pressure liquid;
Quality control;
Matrine;
Ferulic acid;
Shengui anti-pruritic mixture
- From:
International Journal of Traditional Chinese Medicine
2018;40(3):251-257
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the qualitative and quantitative standard of Shengui anti-pruritic mixture. Mehtods Sophorae Flavescentis Radix, Cnidii Fructus, Polygoni Multiflori Radix, Astragali Radix, Paeoniae Radix Alba and Glycyrrhizae Radix Et Rhizoma were identified by TLC.The contents of matrine and ferulic acid were determined by HPLC. Results The TLC showed the obvious characteristics with the spots clear and well-separated with no interference by negative control. Matrine showed a good linear relationship at 0.062 5- 2.500 0 μg (r=0.999 9) with a good meeting of adding sample recovery test. Ferulic acid showed a good linear relationship at 0.021 0-0.840 0 μg (r=0.999 9) with a good meeting of adding sample recovery test. Conclusions The method is easy-operated and accurate which showed a good specificity for the quality control of Shengui anti-pruritic mixture.
