Exosomes:their extraction and its research progress in the diagnosis and treatment of diabetic nephropathy

VernacularTitle:外泌体提取及其在糖尿病肾病诊治中的研究进展
Author: Nan-Nan ZHANG ¹ ; Jin-Sen KANG ; Lin-Lin LI ; Ye WANG ; Xin-Min MAO ; Xue-Jun LI
Author Information

1. 830054乌鲁木齐,新疆医科大学,省部共建中亚高发病成因与防治国家重点实验室
Keywords: exosomes; diabetic nephropathy(DN); extraction; biological markers; vector; therapy
From: Journal of International Pharmaceutical Research 2017;44(10):925-930
CountryChina
Language:Chinese
Abstract: Exosomes are membrane vesicles secreted by various cells containing unique proteins and miRNA from secretory cells.They can reflect the physiological and pathological state of secretory cells,and play an important role in cell-to-cell communica?tion.In recent years,the exosomes have become the focus of research,which brings hope for diseases that can not be treated effective?ly.This review aims to summarize the extraction methods,biological markers of diabetic nephropathy(DN)and the potential of exo?somes as drug carriers,hoping to bring new ideas for future studies on the occurrence and development mechanisms as well as the treat?ment of DN.